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[ACC2010]II型糖尿病病人进行血脂的治疗在预防心血管事件中的作用--Henry Ginsberg教授专访
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国际循环 时间:2010/3/16 17:03:00专题评述(专题) 热点聚焦(专题) 专家访谈(专题)  关键字:II型糖尿病 心血管事件 

  《国际循环》:在临床上,应当如何预防或减少2型糖尿病患者心血管事件的发生?

    Henry Ginsberg:患者应当遵医嘱按时服药。我认为,HbA1c水平要降到接近7%,因为此时发生微血管事件的风险较低。另外,糖尿病患者的收缩压应当降至接近130 mmHg,当然LDL-C应降至100 mg/dl以下。至于是否需要干预HDL-C和TG,我想ACCORD血脂试验给出了答案,合并高TG和低HDL-C的这15%糖尿病患者给予非诺贝特治疗能够得到心血管获益。
 

    <International Circulation>: : At a clinical level how could you prevent or reduce theincidence of CVD among type 2 diabetic patients?

    Dr Henry Ginsberg: They need to follow their doctor’s advice and take their medicines regularly I think the hemoglobin A1c levels should be very close to 7% because that is when micro vascular events are reduced to a sort of flat level, I think their blood pressure should be close to 130 and their LDL levels certainly should be under 100. As to whether their HDL and triglyceride levels should be altered, I think our data suggests that would be of potential benefit in about 15% of diabetic patients with very bad triglyceride elevations and very low HDL levels. 
    



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